F2进口生物反应器/发酵罐系统(F2系列,进口)

型号: F2系列

品牌:西班牙比欧耐特Bionet engineering

产品简介:
F2系列进口发酵罐(生物反应器)用于扩大生物工艺的规模,并用于不同生物技术部门的一系列微生物和细胞培养应用的小型生产应用。在科研与小型工业开发设计应用较多。
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F2系列生物反应器/发酵罐系统包括是原位蒸汽灭菌采(SIP)生物反应器。高品质标准要求下设计和建造的模块化系统,安装操作简单,可轻松便捷整合融入到您工厂工程的生物反应培养设施中。F2系列生物反应器/发酵罐基于其坚实可靠的计和高度自动化、控制、灵活性等 特点基础上制造被广泛用于实验研发和小型工业生产。 

F2系列生物反应器作为标准化的SIP生物反应器,具有专业的设计和施工以及一系列的配置选项,适用于实验室和工业环境,是将生物工艺引入工业环境的主力军。

一、按照容积

F2系列生物反应器/发酵罐系统该系列两种型号(F2-15和F2-30),有效工作容积分别为15升和30升,可能有效工作容积在6到30升之间罐体容器和部件接触产品均由不锈钢A316L制成。多于15个端接口用于仪器扩展、添加测试和尾气。 

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F2-30(30升)

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F2-15(15升)

二、按照通过灭菌

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F2 standard

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F2 autonomous

三、基本配置

1、不同体积的坚固不锈钢容器(Robust stainless steel vessels in different volumes)

这些容器有15升和30升两种,用于微生物处理,盖子、侧面和底部都有端口。

框架尺寸为扩大规模提供了理想的解决方案,因为这两个版本都适合实验室和工业环境。


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The vessels are available in 15 and 30 liter versions for microbial processes, with ports on the lid, side and bottom.

The frame size provides an ideal solution for scale up, as both versions fit in a laboratory and industrial environment.

2、易于清洁的盖子,提供多种端口配置(An easy-to-clean lid providing a variety of port configurations)

盖子的设计提供了广泛的操作可能性,端口的数量为材料和信息交换提供了功能上的多功能性。通过起重机提起盖子,可以轻松清洁、搬运和维护。

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The lid design offers a wide range of possibilities for operation, the number of ports providing functional versatility for material and information exchanges. Easy cleaning, handling and maintenance are enabled by a crane to lift the lid.

3、功能强大且灵活的顶部搅拌模块,易于维护(A powerful and flexible top agitation module with easy maintenance)

一个精确的电机,可同时提供体积和顶部搅拌,以实现搅拌几何结构的灵活性。提供各种转速和不同的涡轮机,如Rushton、Marine和量身定制,以适应不同的需求。

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A precise motor to serve both volumes and top agitation to allow flexibility in agitation geometry. A wide range of rpm and different turbines available, such as Rushton, Marine and tailor-made, to adjust to the different needs.

4、具有一系列泵容量的可扩展和灵活的泵配置(An expandable and flexible pump configuration with a range of pump capacities)

添加模块包括3个蠕动固定速度泵,用于线性和可重复流动,以实现可靠的缩放。

可提供可选的变速附加泵,允许分批、补料分批或连续工艺。此外,这些添加的调整可以通过b权重控制功能的集成来完成。

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The addition module includes 3 peristaltic fixed speed pumps, for linear and repeatable flow to enable reliable scaling.

Optional additional pumps with variable speed are available, allowing for Batch, Fed-Batch or Continuous Processes. Moreover, adjustments of these additions can be done via the integration of bSweight control capabilities.

5、具有灵活控制的精确气体模块,便于缩放(A precise gas module with flexible control for easy scaling)

标准F2装置包括带转子流量计的空气供应、通过喷洒器和叠加供应以及通过反馈回路的高级控制。

不同的附加气体管线及其反馈回路提供了灵活性。MARTA可实现高级控制。

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The standard F2 unit includes Air supply with rotameter, through sparger and overlay supply and with advanced control through feedback loops.

Flexibility is provided by different available additional gas lines with their feedback loops. MARTA enables advanced control.

6、具有经典、简单实用程序管理的高容量集成温度控制(A high capacity integrated temperature control with simple utilities management)

温度控制包括一个夹套,该夹套与生物反应器的内容物形成热交换界面。一个独特的特点是比夹套区域覆盖范围大的扩展。

一回路和二回路的组合确保了容器的良好维护。它们之间有一个热交换器,如果电阻是活动的,或者冷水从冷水箱到夹套,则可以通过热水循环自动加热和冷却。

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Temperature control includes a jacket, which creates the heat exchange interface with the contents of the bioreactor. An unique feature is the large extension than the jacketed area covers.

A combination of a primary and a seconday circuit ensure the good maintenance of the vesssel. There is a heat exchanger between these, to enables automatic heating and cooling through the circulation of hot water if the electrical resistance is active or the cold water from a cold water tank to the jacket.

7、采用高质量传感器进行先进的控制和分析(Advanced control and analysis with high quality sensors)

F2配备了传感器,如pH、DO、温度和液位,以及一系列其他可用的附加传感器。这些能够实现可靠的测量、监控、数据分析和先进的控制策略。

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The F2 comes with sensors, such as pH, DO, temperature and level, as well as a range of other available additional sensors. These enable reliable measurements, monitorization, data analysis and advanced control strategies.

8、可靠的冷凝器和排气管线压力控制(Reliable condenser and pressure control for exhaust gas line)

管壳式冷凝器,以及手动针阀和电磁阀,包括在废气中,以控制压力和湿度。

自动压力控制、废气过滤或加热器可作为可选的附加组件。

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Shell and tube condenser, as well as manual needle and solenoid valves included in exhaust gas in order to control pressure and moisture.

Automatic pressure control, exhaust gas filtering or heater can be included as optional Add-Ons.

9、可重新灭菌取样阀,便于在操作过程中进行快速无菌取样(Re-sterilizable sampling valve to facilitate rapid and sterile sampling during operation)

F2设备的取样阀允许在工艺过程中进行多次取样,包括手动蒸汽阀和带疏水阀的蒸汽冷凝水出口。阀门可重新消毒。

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The sampling valve of the F2 equipment allows for multiple sampling during process, including a manual steam valve and steam condensate outlet with steam trap. The valve is re-sterilizable.

10、易于使用的就地灭菌(SIP),便于操作(Easy-to-use Sterilization in Place (SIP) to facilitate operation)

F2有两种可选的灭菌版本:标准灭菌版本和自主灭菌版本,自主灭菌版本作为可选的附加组件提供。

包括一个小型蒸汽发生器,用于输送、添加、收获和取样管线的灭菌。

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The F2 is available in two alternative sterilization versions: standard and autonomous, the autonomous being available as an optional Add-On.

A small steam generator is included for the sterilization of the transfer, addition, harvest and sampling lines.

11、具有连接到BCU的触摸式PC和MARTA软件许可证(Includes a touch PC attached to the BCU and a license of MARTA software)

MARTA是在SIEMENS WINCC平台上开发的,以保证特定过程数据的高级控制、可视化和注册,并可选择通过附加模块升级自动化功能。

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MARTA has been developed on SIEMENS WINCC platform to guarantee advanced control, visualization and registry of data of the specific process, with the option of upgrading automation functions with additional modules.

12、可根据GMP指南进行设计、建造和鉴定(Can be designed, built and qualified under GMP guidelines)

我们的GMP方法是结构化的,因此设计、施工和控制可以适应您的特定项目和监管需求,以便验证您从标准到GMP的流程。

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Our GMP approach is structured so that design, construction and control can be adapted to your specific project and regulatory needs to allow the validation of your processes from standard to GMP.

13、可移动式设计(Frame with wheels to facilitate mobility)

F2生物反应器通过标准门安装,可以位于实验室或工业环境中。框架中的轮子进一步促进了该生物反应器在实验室或工业环境中作为多用途生物反应器的使用。

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The F2 bioreactor fits in through a standard doors and can be located in either a lab or industrial environment. The wheels in the frame further facilitate th euse of this bioreactor as a multipurpose bioreactor in lab or industrial .

14、未来扩展的可能性-即插即用

未来扩展的可能性-即插即用,可访问的备用信号和有线连接器的存在允许未来以即插即用的方式集成额外的仪器和执行器以及Bionet的bSmart模块。

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Possibilities for future expansion – Plug&Play

context.The presence of accessible spare signals and wired connectors allows for future integration of additional instrumentation and actuators, and Bionet’s bSmart Modules in a Plug&Play fashion.





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